Meeting program

12:30 – 12:45  Opening and welcome

• Elizabeth Macintyre (France) & Margarita Guenova (Bulgaria)

12:45 – 14:45 Session 1: Integrated diagnosis – translating data to decisions

Chair to be announced

• Keynote lecture: Integrated diagnostics in 2030: From parallel testing to a clinically actionable, reimbursed report
  Speaker to be announced
• Genomic classification and risk assessment: Are molecular categories replacing traditional diagnosis and what did WHO5 teach us?
  Caroline Cargo (United Kingdom)
• Somatic vs germline – Integrating predisposition testing into diagnostic workflows
  Speaker to be announced
• Case study
  Speaker to be announced

14:45 – 15:15 Coffee break

15:15 – 17:00 Session 2: Building an integrated diagnostic service

Chair to be announced

• Clinical pathway integration – embedding integrated Diagnostics into MDTs and care pathways
  Tom Butler (United Kingdom)
• Bioinformatic integration and data standards – Making multimodal data interpretable and shareable
  Speaker to be announced
• Functional precision medicine and composite biomarkers – The next diagnostic frontier
  Ludovic Lhermitte (France)
• Case study
  Speaker to be announced

17:00 – 17:15 Coffee break

17:15 – 18:00 Satellite Symposium 1

18:00 – 19:00 Welcome reception & poster session

09:00 – 10:45 Session 3: AI and multimodal diagnostics: From impressive performance to safe clinical use

Chair to be announced

• AI-supported cytomorphology: What is already ready for routine use?
  Speaker to be announced
• Tissue based: Digital and computational pathology — from image analysis to integrated reporting
  Daniel Royston (United Kingdom)
• AI-assisted flow cytometry
  Yvan Saeys (Belgium)
• Case study
  Speaker to be announced

10:45 – 11:00 Coffee break

11:00 – 12:45 Session 4: Can we turn IVDR into an advantage at the European level?

Chair to be announced

• Implementation and regulatory science for diagnostics: What should hematologists understand, and how can we contribute?
  Tom Melvin (Ireland)
• IVDR and in-house diagnostic devices: What has or will change for academic laboratories?
  Elizabeth Macintyre (France)
• Regulatory paths to market of AI-assisted diagnostic systems
  Speaker to be announced
• Case study
  Speaker to be announced

12:45 – 13:30 Lunch break

13:30 – 15:15 Session 5: What is needed to base a clinical decision on IVD results?

Chair to be announced

• From comparable to trustworthy: What can standardization and smarter EQA add to flow cytometry?
  Jacques van Dongen (Netherlands)
• NGS-based diagnostics: from analytical validation to clinical decision-making
  Torsten Haferlach (Germany)
• MRD across diseases and technologies: Harmonisation and clinical integration, including ctDNA and surrogacy intoduction to session 6 / should we move toward common reporting principles?
  Monika Brüggemann (Germany)
• Case study
  Speaker to be announced

15:15 – 15:30 Coffee break

15:30 – 17:15 Session 6: HTA of diagnostics

Chair to be announced

• From test to diagnostic pathway value: how should integrated dignostics be assessed and why do diagnostics not fit in to HTA for pharmaceuticals?
  Bernard Wörmann (Germany)
• What evidence do payers need before reimbursing a new diagnostic pathway? Including bundled billing and value-based diagnostics
  Isabelle Durand-Zaleski (France)
• Surrogate endpoints as a value currency: can MRD-negativity justify paying for the test?
  Ciro Botta (Italy)
• Case study
  Speaker to be announced

17:15 – 18:00 Satellite Symposium 2

09:00 – 10:45 Session 7: Scaling access and expertise across Europe and beyond

Chair to be announced

• Mapping diagnostic inequalities in Europe
  Margarita Guenova (Bulgaria)
• What access means to patients (time, travel, uncertainty and lost treatment opportunities) plus a financiers viewpoint on diagnostic HTA
  Peter Kapitein (Netherlands)
• Harmonizing hematology diagnostic data across borders: Opportunities and responsibilities under the European Health Data Space framework
  Kimmo Porkka (Finland)
• Case study
  Speaker to be announced

10:45 – 11:00 Coffee break

11:00 – 12:30 Session 8: Future directions and roadmap

Chair to be announced

• Keynote lecture: The strategic value of integrated diagnostics in accelerating the global fight against cancer
  Speaker to be announced
• Panel discussion: A European roadmap for diagnostic hematology in the next 5 years
  All speakers

12:30 – 12:45 Takeaways and closing

• Elizabeth Macintyre (France) & Margarita Guenova (Bulgaria)

12:45 – 13:30 Farewell lunch