08:00 - 08:55 Meet the Experts Breakfast*
- Current management of Myelofibrosis
C Harrison (United Kingdom)
- Current management of AML
H Döhner (Germany)
- Current management of MDS
A Giagounidis (Germany)
*Registration required
09:00 - 10:00 Session 3: Genomics in MPN, MDS, AML
Chair: A Mead (United Kingdom)
- Driver mutations associated with MDS and MPN; any commonality?
F Solé (Spain)
- Genetics of AML and MDS; how different?
M Della Porta (Italy)
- Panel discussion
All speakers
10:00 - 11:15 Session 4: HSC Niche
Chair: D Bonnet (United Kingdom)
- The HSC niche in aging
H Geiger (Germany)
- HSCs under inflammatory stress
M Essers (Germany)
- Dissecting niche dependencies during leukemogenesis
D Bonnet (United Kingdom)
- Panel discussion
All speakers
11:15 - 11:45 Coffee break
11:45 - 13:00 Session 5: Immunome in MPN, MDS and AML
Chair: A Van de Loosdrecht (The Netherlands)
- Immunome for patient stratification; lessons from solid tumours and psychosis
A Hayday (United Kingdom)
- Inflammation in MPN, MDS and AML; a driving force?
M Raaijmakers (The Netherlands)
- Cellular Immune response in MPN, MDS and AML; Cause or Consequence?
S Kordasti (United Kingdom)
- Panel discussion
All speakers
13:00 - 14:30 Lunch break
13:30 - 14:30 GSK Satellite Symposium: Evolving Treatments for Cytopenic Myelofibrosis
- Welcome and Introduction
MF McMullin (United Kingdom)
- Cytopenias in Myelofibrosis: Understanding the Challenges
MF McMullin (United Kingdom)
- Current and Emerging Treatment Options for Patients With Myelofibrosis and Anemia and/or Thrombocytopenia
A Mead & MF McMullin (United Kingdom)
- Panel discussion/ Q&A
A Mead (moderator)
14:30 - 15:45 Session 6: Development of biomarkers of disease progression
Chair: K Döhner (Germany)
- AML MRD in 2023
J Cloos (The Netherlands)
- Clonal Evolution and the development of Myeloid Malignancies
J Jansen (The Netherlands)
- Allele burden and prognosis in MPN
A Mead (United Kingdom)
- Panel discussion
All speakers
15:45 - 16:15 Coffee break
16:15 - 17:15 Session 7: Translating Omics to diagnostic tests
- Building prognostic and predictive models using big data
K Porkka (Finland)
- Genomics for patients' stratification in MPN
A Mead (United Kingdom)
- Panel discussion
All speakers
17:15 - 17:45 Debate: Cytometry versus Morphology, time to move on?
Chair: S Kordasti (United Kingdom)
- Pro: A Van de Loosdrecht (The Netherlands)
- Con: S Loghavi (United States)
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