Meeting program
Friday, April 25 - EHA-Balkan Hematology Day 2025
09:00 - 10:05 Opening session
- Welcome of participants
Dimitar Efremov (North Macedonia/Italy) - Introduction of meeting program
Irina Panovska-Stavridis (North Macedonia) - History of the Balkan Hematology Association
Oliver Karanfilski (North Macedonia) - EHA and History of Balkan Hematology Day
Gianluca Gaidano (Italy) - Recent regional developments in the treatment of lymphoma
Irina Panovska-Stavridis (North Macedonia) - CART program
Biljana Todorova (Slovenia)
10:05 - 10:30 Coffee break
10:30 - 12:00 Session 1: Mantle-cell lymphoma
Chairs: Georg Hess (Germany) & Svetlana Krstevska-Balkanov North Macedonia)
- State-of-the-Art lecture
Georg Hess (Germany) - Indolent mantle cell lymphoma
Darko Antic (Serbia) - Obinutuzumab in combination with targeted therapies in the treatment of relapsed mantle-cell lymphoma
Nevenka Ridova (North Macedonia) - Is autologous stem cell transplantation still an option for the treatment of mantle cell lymphoma?
Murat Özbalak (Türkiye) - Panel discussion
All speakers
12:00 - 12:45 Octapharma Corporate symposium: “Secondary Immunodeficiency"
Chair: Svetlana Kocheva (Skopje)
- Characteristics and management of immunodeficiency in lymphoproliferative diseases
Goran Marjanović (Serbia)
12:45 - 13:30 Lunch break
13:30 - 15:00 Session 2: Hodgkin lymphoma
Chairs: Sirpa Lëppa (Finland) & Oliver Karanfilski (North Macedonia)
- State-of-the-Art lecture
Sirpa Lëppa (Finland) - HIV - Associated Hodgkin's lymphoma Prognosis and Therapy
Miranda Hoti (Kosovo) - Immune checkpoint inhibitors in Hodgkin’s lymphoma - When and how?
Hristina Ivanova (Bulgaria) - Where are we in late relapse Hodgkin lymphoma?
Merve Ecem Erdoğan Yön (Türkiye) - Unusual Primary Bone Marrow Hodgkin Lymphoma Presentation
Fitim Gashi (Kosovo) - Panel discussion
All speakers
15:00 - 16:30 Session 3: Large B cell lymphomas
Chairs: Maria Gomes da Silva (Portugal) & Aleksandar Stojanovic (North Macedonia)
- State-of-the-Art lecture
Maria Gomes da Silva (Portugal) - Prognostic Significance and In Vivo Modelling of Cluster 2 DLBCL
Ivan Negara (Moldova/Italy) - Inflammation and inflammatory prognostic indices in Diffuse large B-cell lymphomas
Zorica Cvetković (Serbia) - Prognostic significance of CD 47 expression in patients with newly diagnosed Large B cell lymphoma
Ilija Bukurecki (Serbia) - What treatment for DLBCL in 2025?
Alma Cili (Albania) - Panel discussion
All speakers
16:30 - 17:00 Coffee break
17:00 - 18:40 Session 4: Marginal Zone Lymphoma
Chairs: Martin Ivanovski (North Macedonia) & Laze Cadievski (North Macedonia)
- State-of-the-Art lecture
Anastasios Stathis (Switzerland) - Diagnosis & treatment of nodal marginal zone lymphoma
Zdravko Mitrović (Croatia) - Approach to extranodal marginal zone lymphoma
Selin Küçükyurt Kaya (Türkiye) - Successful treatment of extranodal marginal zone lymphoma with kidney affection- case report
Laze Cadievski (North Macedonia) - Our experience with primary refractory extranodal marginal zone lymphoma
Bozhidar Kochovski (North Macedonia) - How to manage Waldenstrom's Macroglobulinemia in 2025
Evdoxia Hatjiharissi (Greece) - Panel discussion
All speakers
Saturday, April 26 - National Congress of the Macedonian Hematology Association
09:00 - 11:00 Classification, diagnosis, genetic subtyping and monitoring of lymphoid malignancies
Chairs: Gordona Petrusevska (Northa Macedonia) & Aleksandar Dimovski (North Macedonia)
- Classification of B-cell lymhoproliferative disorders
Andreas Rosenwald (Germany) - Genomic profiling of lymphoid neoplasms
Richard Rosenquist (Sweden) - Stereotyped B-Cell Receptors in B-Cell Lymphomas
Kostas Stamatopoulos (Greece) - Liquid biopsy of lymphoma
Gianluca Gaidano (Italy)
11:00 - 11:30 Coffee break
11:30 - 13:30 Advances in the biology and treatment of chronic lymphocytic leukemia
Chairs: Lidija Cevreska (North Macedonia) & Dimitar Efremov (Italy)
- New insights in the biology of CLL
Nicholas Chiorazzi (United States) - First line CLL treatment
Luca Laurenti (Italy) - Mechanisms of resistance to targeted therapies and Richter transformation
Dimitar Efremov (Italy) - Treatment of relapsed/refractory CLL and Richter transformation
Gianluca Gaidano (Italy)
13:30 - 14:00 Corporate symposium “New generation of potent BTK Inhibitors for treatment of CLL”
Chair: Dimitar Efremov (North Macedonia/Italy)
- BTK inhibitors similarities and differences
Dimitar Efremov (North Macedonia/Italy) - Acalabrutinib, a BTK inhibitor for treatment of CLL
Alessandra Tedeschi (Italy) - Discussion
All speakers
14:00 - 15:00 Lunch break
15:00 - 17:00 Advances in the treatment of FL, HCL, WM and MM
Chairs: Irina Panovska-Stavridis (North Macedonia), Aleksandra Pivkova-Veljanovska (North Macedonia)
- Advances in the biology and treatment of follicular lymphoma
Francesco Forconi (United Kingdom) - Current and future therapies for Hairy Cell Leukemia
Enrico Tiacci (Italy) - Treatment of Waldenstrom's Macroglobulinemia
Alessandra Tedeschi (Italy) - Current and future therapies for Multiple Myeloma
Francesca Gay (Italy)
17:00-18:30 Pediatric and patient advocacy session
Chair: Kocheva Svetlana (North Macedonia)
18:30 - 19:15 Poster session & Farwell drink
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