Subconjunctival injection of mesenchymal stromal cells protects the cornea in an experimental model of GVHD. Martínez-Carrasco R, Sánchez-Abarca LI, Nieto-Gómez C, García EM, Sánchez-Guijo F, Argüeso P, Aijón J, Hernández-Galilea E, Velasco A. Ocul Surf. 2019 Jan 7. pii: S1542-0124(18)30382-3. doi: 10.1016/j.jtos.2019.01.001. [Epub ahead of print]
Human Bone Marrow Mesenchymal Stromal Cells Promote Bone Regeneration in a Xenogeneic Rabbit Model: A Preclinical Study. Blanco JF, García-Briñon J, Benito-Garzón L, Pescador D, Muntión S, Sánchez-Guijo F. Stem Cells Int. 2018 Jul 5;2018:7089484. doi: 10.1155/2018/7089484. eCollection 2018.
Second-line treatment for acute graft-versus-host disease with mesenchymal stromal cells: A decision model. Thielen FW, Blommestein HM, Oosten LEM, Calkoen FG, Lankester AC, Zwaginga JJ, Le Blanc K, Redondo A, Sánchez-Guijo F, Algeri M, Locatelli F, Fibbe WE, Uyl-de Groot CA. Eur J Haematol. 2018 Aug 6. doi: 10.1111/ejh.13158. [Epub ahead of print]
Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: long-term follow up of a multicenter randomized controlled clinical trial (phase I/II). Lamo-Espinosa JM, Mora G, Blanco JF, Granero-Moltó F, Núñez-Córdoba JM, López-Elío S, Andreu E, Sánchez-Guijo F, Aquerreta JD, Bondía JM, Valentí-Azcárate A, Del Consuelo Del Cañizo M, Villarón EM, Valentí-Nin JR, Prósper F. J Transl Med. 2018 Jul 31;16(1):213. doi: 10.1186/s12967-018-1591-7.
Manufacturing Mesenchymal Stromal Cells for the Treatment of Graft-versus-Host Disease: A Survey among Centers Affiliated with the European Society for Blood and Marrow Transplantation. Trento C, Bernardo ME, Nagler A, Kuçi S, Bornhäuser M, Köhl U, Strunk D, Galleu A, Sanchez-Guijo F, Gaipa G, Introna M, Bukauskas A, Le Blanc K, Apperley J, Roelofs H, Van Campenhout A, Beguin Y, Kuball J, Lazzari L, Avanzini MA, Fibbe W, Chabannon C, Bonini C, Dazzi F. Biol Blood Marrow Transplant. 2018 Nov;24(11):2365-2370. doi: 10.1016/j.bbmt.2018.07.015. Epub 2018 Jul 20.
Sequential intravenous allogeneic mesenchymal stromal cells as a potential treatment for thromboangiitis obliterans (Buerger's disease). Martin-Rufino JD, Lozano FS, Redondo AM, Villaron EM, Rueda R, Fernandez-Samos R, Sanchez-Guijo F. Stem Cell Res Ther. 2018 May 30;9(1):150. doi: 10.1186/s13287-018-0901-6.
Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease? Broekman W, Khedoe PPSJ, Schepers K, Roelofs H, Stolk J, Hiemstra PS. Thorax. 2018 Jun;73(6):565-574. doi: 10.1136/thoraxjnl-2017-210672. Epub 2018 Apr 13. Review.
Mesenchymal Stromal Cell Irradiation Interferes with the Adipogenic/Osteogenic Differentiation Balance and Improves Their Hematopoietic-Supporting Ability. Preciado S, Muntión S, Rico A, Pérez-Romasanta LA, Ramos TL, Ortega R, Borrajo J, Corchete LA, Rodríguez C, Díez-Campelo M, Sánchez-Abarca LI, Del Cañizo MC, Sánchez-Guijo F. Biol Blood Marrow Transplant. 2018 Mar;24(3):443-451. doi: 10.1016/j.bbmt.2017.11.007. Epub 2017 Nov 16.
Mesenchymal stromal cells induce a permissive state in the bone marrow that enhances G-CSF-induced hematopoietic stem cell mobilization in mice. de Kruijf EFM, Zuijderduijn R, Stip MC, Fibbe WE, van Pel M. Exp Hematol. 2018 Aug;64:59-70.e2. doi: 10.1016/j.exphem.2018.05.002.
Mesenchymal stromal cells for acute graft-versus-host disease: response at 1 week predicts probability of survival. Galleu A, Milojkovic D, Deplano S, Szydlo R, Loaiza S, Wynn R, Marks DI, Richardson D, Orchard K, Kanfer E, Tholouli E, Saif M, Sivaprakasam P, Lawson S, Bloor A, Pagliuca A, Potter V, Mehra V, Snowden JA, Vora A, Kishore B, Hunter H, Apperley JF, Dazzi F. Br J Haematol. 2019 Jan 13. doi: 10.1111/bjh.15749. [Epub ahead of print]
Bi-directional cell-pericellular matrix interactions direct stem cell fate. Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E. Nat Commun. 2018 Oct 3;9(1):4049. doi: 10.1038/s41467-018-06183-4. Erratum in: Nat Commun. 2018 Nov 14;9(1):4851. Nat Commun. 2018 Dec 18;9(1):5419.
Mesenchymal-myeloid interaction in the regulation of immunity. Cheung TS, Dazzi F. Semin Immunol. 2018 Feb;35:59-68. doi: 10.1016/j.smim.2018.01.002. Epub 2018 Feb 1. Review.
Advances in mesenchymal stromal cell therapy in the management of Crohn's disease. Ibraheim H, Giacomini C, Kassam Z, Dazzi F, Powell N. Expert Rev Gastroenterol Hepatol. 2018 Feb;12(2):141-153. doi:10.1080/17474124.2018.1393332. Epub 2017 Nov 2. Review.
Intelligent Photosensitive Mesenchymal Stem Cells and Cell-Derived Microvesicles for Photothermal Therapy of Prostate Cancer. Huang L, Xu C, Xu P, Qin Y, Chen M, Feng Q, Pan J, Cheng Q, Liang F, Wen X, Wang Y, Shi Y, Cheng Y. Nanotheranostics. 2018 Nov 11;3(1):41-53. doi: 10.7150/ntno.28450. eCollection 2019.
Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases. Shi Y, Wang Y, Li Q, Liu K, Hou J, Shao C, Wang Y. Nat Rev Nephrol. 2018 Aug;14(8):493-507. doi: 10.1038/s41581-018-0023-5. Review.
Phenotypic and functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome. Starc N, Li M, Algeri M, Conforti A, Tomao L, Pitisci A, Emma F, Montini G, Messa P, Locatelli F, Bernardo ME, Vivarelli M. Cytotherapy. 2018 Mar;20(3):322-334. doi: 10.1016/j.jcyt.2017.12.001. Epub 2017 Dec 29.
Lymphoproliferative disease in the rectum 4 years after local mesenchymal stromal cell therapy for refractory perianal Crohn's fistulas: a case report. Barnhoorn MC, van Halteren AGS, van Pel M, Molendijk I, Struijk AC, Jansen PM, Verspaget HW, Dijkstra G, Oosten LEM, van der Meulen-de Jong AE. J Crohns Colitis. 2018 Dec 18. doi: 10.1093/ecco-jcc/jjy220. [Epub ahead of print]
Therapeutic potential of stromal cells of non-renal or renal origin in experimental chronic kidney disease. Rota C, Morigi M, Cerullo D, Introna M, Colpani O, Corna D, Capelli C, Rabelink TJ, Leuning DG, Rottoli D, Benigni A, Zoja C, Remuzzi G. Stem Cell Res Ther. 2018 Aug 14;9(1):220. doi: 10.1186/s13287-018-0960-8.
Mesenchymal Stromal Cell Therapy for Solid Organ Transplantation. Reinders MEJ, van Kooten C, Rabelink TJ, de Fijter JW. Transplantation. 2018 Jan;102(1):35-43. doi: 10.1097/TP.0000000000001879. Review.
Allogeneic Mesenchymal Stromal Cells (MSCs) are of Comparable Efficacy to Syngeneic MSCs for Therapeutic Revascularization in C57BKSdb/db Mice Despite the Induction of Alloantibody. Liew A, Baustian C, Thomas D, Vaughan E, Sanz-Nogués C, Creane M, Chen X, Alagesan S, Owens P, Horan J, Dockery P, Griffin MD, Duffy A, O'Brien T. Cell Transplant. 2018 Aug;27(8):1210-1221. doi: 10.1177/0963689718784862. Epub 2018 Jul 17.
Syndecan-2-positive, Bone Marrow-derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats. Masterson C, Devaney J, Horie S, O'Flynn L, Deedigan L, Elliman S, Barry F, O'Brien T, O'Toole D, Laffey JG. Anesthesiology. 2018 Sep;129(3):502-516. doi: 10.1097/ALN.0000000000002327.
3-month Safety Assessment of Human Bone Marrow Derived Mesenchymal Stromal Cells Administered Once by the Intramuscular Route to Immunodeficient Mice. Creane M, McElroy M, Duffy A, Dawood CS, O'Brien T. Toxicol Pathol. 2018 Apr;46(3):290-301. doi: 10.1177/0192623318760516. Epub 2018 Mar 4.
Anti-donor antibody induction following intramuscular injections of allogeneic mesenchymal stromal cells. Alagesan S, Sanz-Nogués C, Chen X, Creane M, Ritter T, Ceredig R, O'Brien T, Griffin MD. Immunol Cell Biol. 2018 May;96(5):536-548. doi: 10.1111/imcb.12024. Epub 2018 Mar 23.
Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379. O'Brien KP, Khan S, Gilligan KE, Zafar H, Lalor P, Glynn C, O'Flatharta C, Ingoldsby H, Dockery P, De Bhulbh A, Schweber JR, St John K, Leahy M, Murphy JM, Gallagher WM, O'Brien T, Kerin MJ, Dwyer RM. Oncogene. 2018 Apr;37(16):2137-2149. doi: 10.1038/s41388-017-0116-9. Epub 2018 Jan 25.
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