Specialized Working Group on Myelodysplastic Syndromes (MDS)

Overview

The MDS SWG focuses on the promotion and exchange of scientific and clinical evidence, ideas, and projects in the field of MDS.  

We foster collaboration and connection between clinicians across Europe and beyond—especially in terms of common clinical studies and translational research.  

We have the additional responsibility of reviewing and, where necessary, reworking current guidelines in MDS.  

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Subcommittee on Bone Marrow Failure (BMF) immunology 

The MDS SWG includes the subcommittee on BMF immunology.  

Dysregulated immune response is becoming an increasingly important part of bone marrow failure syndromes (BMFs) pathophysiology. In acquired aplastic anemia, this can involve a combination of dysfunctional immunoregulation and active cellular immune response. In high-risk MDS, patients might experience an immunosuppression feature and smoldering myeloid-derived inflammation. 

Some evidence also suggests that immune signatures not only have prognostic value but could also be used: 

• For patient stratification  
• As predictors for response to therapy  

The aim of the BMF immunology subcommittee is to coordinate scientific activities within European centers and facilitate collaboration and connection. 

The subcommittee consists of experts (clinicians and scientists) in the field of bone marrow failure immunology, with specific emphasis on: 

• MDS 
• Acquired aplastic anemia  
• Paroxysmal nocturnal hemoglobinuria (PNH) 

The aims of the BMF immunology subcommittee are:  

• To form a working group of expertise to identify areas of clinical and fundamental research 
• To promote research activities through organizing events, workshops, or training sessions within EHA meetings 
• To evaluate and suggest new diagnostic tests and scoring systems for patient stratification 
• To evaluate, suggest, and participate in clinical trials to facilitate recruitment and related research projects  
• To support next generation hematologists with interests in bone marrow failure immunology through networking opportunities and providing financial support  
• Find out more about we advance MDS treatment and understanding through the i4MDS consortium.
  

Join us

If you work in our field and share our mission to advance our understanding of MDS, you’d be welcome to join our SWG. However, before you apply, we recommend you read our application guidance.

Ready? Apply now on the EHA Portal.

If you have any questions, please email our SWGs team.