Meeting program

13:00–13:15 Opening and welcome

13:15–15:15 Session 1: HSC ageing

  • Ageing of the BM microenvironment
    Cesar Nombela-Arrieta (Switzerland)
  • Immuno-ageing
    Claudia Waskow (Germany)
  • Metabolic reprogramming aged HSCs
    Nicola Vannini (Switzerland)

15:15–16:00 Coffee break

16:00–17:30 Workshop 1: Strategies to prevent, delay or reverse ageing

  • Experimental clonal tracing in ageing
    Alejo Rodriguez-Fraticelli (Spain)
  • Extrinsic factors regulating HSC aging and opportunities for intervention
    Maria Carolina Florian (Spain)

18:00–19:00 Welcome Reception

09:00–11:00 Session 2: Senescence

  • Cellular senescence in ionizing radiation (IR) and chemotherapy induced normal tissue damage
    Daohong Zhou (United States)
  • Senescence in myeloid malignancies and HSCs
    Raffaella Di Micco (Italy)
  • Lecture title to be announced
    Adele Fielding (United Kingdom)

11:00–11:30 Coffee break

11:30–13:00 Workshop 2: Clinical opportunities of senolytics in hemato-oncology

  • Senescence in cancer
    Manuel Collado (Spain)
  • Therapeutic opportunities for senescence in lymphoma or other cancers
    Clemens Schmitt (Germany)

13:00–14:00 Lunch break

14:00–16:00 Session 3: Clonal hematopoiesis

  • Mouse models of CH
    Jennifer Trowbridge (United States)
  • Lecture title to be announced
    Speaker to be announced
  • AI in preventative medicine
    Matteo della Porta (Italy)

16:00–16:30 Coffee break

16:30–18:00 Workshop 3: CHIP in the clinic

  • The aging of the blood system and leukemia diagnosis from the peripheral blood
    Liran Shlush (Israel)
  • CHIP, hematology and cardiovascular disease
    Jose Javier Fuster (Spain)

09:00–10:30 Workshop 4: Challenges and recommendations for the translation of biomarkers of ageing

  • Epigenetic aging and adverse effects in UK based populations
    Riccardo Marioni (United Kingdom)
  • Validation of ageing biomarkers
    Chiara Herzog (United Kingdom)
  • Lecture title to be announced
    Speaker to be announced

10:30–11:00 Coffee break

11:00–12:30 Session 5: Clinical trials

  • Artificial Intelligence to generate synthetic patient cohorts to serve as control groups in virtual clinical trials
    Alfonso Piciocchi (Italy)
  • Interventions/Clinical trials in CH
    Kirsten Grønbæk (Denmark)

12:30–12:45 Takeaways and closing

12:45–13:30 Farewell lunch