Meeting program
13:00–13:15 Opening and welcome
13:15–15:15 Session 1: HSC ageing
- Ageing of the BM microenvironment
Cesar Nombela-Arrieta (Switzerland) - Immuno-ageing
Claudia Waskow (Germany) - Metabolic reprogramming aged HSCs
Nicola Vannini (Switzerland)
15:15–16:00 Coffee break
16:00–17:30 Workshop 1: Strategies to prevent, delay or reverse ageing
- Experimental clonal tracing in ageing
Alejo Rodriguez-Fraticelli (Spain) - Extrinsic factors regulating HSC aging and opportunities for intervention
Maria Carolina Florian (Spain)
18:00–19:00 Welcome Reception
09:00–11:00 Session 2: Senescence
- Cellular senescence in ionizing radiation (IR) and chemotherapy induced normal tissue damage
Daohong Zhou (United States) - Senescence in myeloid malignancies and HSCs
Raffaella Di Micco (Italy) - Lecture title to be announced
Adele Fielding (United Kingdom)
11:00–11:30 Coffee break
11:30–13:00 Workshop 2: Clinical opportunities of senolytics in hemato-oncology
- Senescence in cancer
Manuel Collado (Spain) - Therapeutic opportunities for senescence in lymphoma or other cancers
Clemens Schmitt (Germany)
13:00–14:00 Lunch break
14:00–16:00 Session 3: Clonal hematopoiesis
- Mouse models of CH
Jennifer Trowbridge (United States) - Lecture title to be announced
Speaker to be announced - AI in preventative medicine
Matteo della Porta (Italy)
16:00–16:30 Coffee break
16:30–18:00 Workshop 3: CHIP in the clinic
- The aging of the blood system and leukemia diagnosis from the peripheral blood
Liran Shlush (Israel) - CHIP, hematology and cardiovascular disease
Jose Javier Fuster (Spain)
09:00–10:30 Workshop 4: Challenges and recommendations for the translation of biomarkers of ageing
- Epigenetic aging and adverse effects in UK based populations
Riccardo Marioni (United Kingdom) - Validation of ageing biomarkers
Chiara Herzog (United Kingdom) - Lecture title to be announced
Speaker to be announced
10:30–11:00 Coffee break
11:00–12:30 Session 5: Clinical trials
- Artificial Intelligence to generate synthetic patient cohorts to serve as control groups in virtual clinical trials
Alfonso Piciocchi (Italy) - Interventions/Clinical trials in CH
Kirsten Grønbæk (Denmark)
12:30–12:45 Takeaways and closing
12:45–13:30 Farewell lunch