2023 winners

Topic: The role of transcriptional adaptor proteins in haematopoietic stem cell expansion and inflammation University of Oxford United Kingdom

Topic: Targeting the dysregulated metabolic program in acute myeloid leukemia University Milano-Bicocca Italy

Topic: Targeting the aged bone marrow niche to rejuvenate hematopoiesis following acute stress Goethe University Hospital Frankfurt Germany

Topic: Exploiting cell-intrinsic inflammatory signaling in acute myeloid leukemia as a therapeutic strategy University Hospital Zurich Switzerland

Title: Mitochondria-containing Erythrocytes in Sickle Cell Anemia: Characterization and Therapeutic Opportunities University of Patras Greece

Topic: Targeting the hematopoietic stem cell niche to improve gene therapy for hemoglobinopathies Fondazione Telethon ETS Italy

Topic: Endoplasmic Reticulum Stress in the Acute Myeloid Leukaemia microenvironment Barts Cancer Institute United Kingdom

Topic: Endoplasmic Reticulum Stress in the Acute Myeloid Leukaemia microenvironment Cochin Institute France

Topic: Functional insights into clonal haematopoiesis mutations University of Veterinary Medicine Austria

Topic: Functional insights into clonal haematopoiesis mutations University of Glasgow United Kingdom

Topic: State-of-the-art Human HSC cultures: improving HSC expansion, niche-in-a-dish and new frontiers in culture conditions German Cancer Research Center (DKFZ) Germany

Topic: State-of-the-art Human HSC cultures: improving HSC expansion, niche-in-a-dish and new frontiers in culture conditions York Biomedical Research Institute United Kingdom

Topic: START project: Self-amplifying RNA-engineered T cells for Anti-leukemic Redirected Therapy University of Antwerp Belgium

Topic: Clonal Hematopoiesis of Indeterminate Potential (CHIP): role of heterochromatin disorganization and Transposable Element Activation? INSERM France

Topic: Regulation of Hematopoietic Stem Cells by Bone Marrow Memory CD8 T Cells University of Zurich Switzerland

Topic: CAR macrophages with sustained M1 phenotype: deceiving the tumor immunosuppressive microenvironment with deception receptors. Hospital General Universitario Santa Lucía Spain

Topic: Kicking of the contribution of “Preleukemic Dendritic Cells” in clonal hematopoiesis associated pathologies The Francis Crick Institute United Kingdom

Topic: NeuroNK - Neuronal control of natural killer cells Maastricht University Medical Center The Netherlands

Topic: Structural analysis of the B cell receptor immunoglobulin in B cell lymphomas Institute of Applied Biosciences, Center for Research and Technology Hellas (INAB|CERTH) Greece

Topic: Single cell genomics in CLL treated with targeted therapies Semmelweis University Hungary

Topic: Impact of the tumor microenvironment in influencing (Chimeric Antigen Receptor) CAR T cells activity in B-Cell Acute Lymphoblastic Leukemia University of Milano-Bicocca, Italy

Topic: Perfusion of hemoglobin based oxygen carriers in organs-on-chip models Technical University of Denmark Denmark

Topic: Analysis of spatial distribution of hematopoietic stem and progenitor cells in the bone marrow niche during steady-state and inflammaging Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) Germany

Topic: Bottom-up manufacturing of artificial anti-tumor T cells Katholieke Universiteit Leuven Belgium

Topic: Improvement of the in vitro culture of P. vivax field isolates Institut Pasteur France

Topic: Development of novel adoptive cell therapy: CAR-CIML-NK cells with enhanced anti-tumor targeting and killing capacities and immune cell modulation NOVA Medical School of NOVA University of Lisbon Portugal

Topic: Ex vivo drug testing to identify novel therapeutic options for the CDX2/UBTF high-risk leukaemia Université Paris-Cité France

Topic: Regulation of human bone marrow hematopoietic stem cell function by MLLT3 isoforms University of Helsinki Finland

Topic: Molecular programs of blood stem cell fate: how to break the self-renewal loop? The University of York United Kingdom