Meeting Program
13:00–13:15 Opening and welcome
- Words of welcome
Konstanze Döhner (Germany)
Claire Harrison (United Kingdom)
Shahram Kordasti (United Kingdom)
13:15–14:15 Session 1: Diagnosis, Classification and Risk Assessment in 2026
Chair: Catherine Cargo (United Kingdom)
- Acute myeloid leukemia
Hartmut Döhner (Germany) - Myeloproliferative neoplasms
Lina Benajiba (France) - Myelodysplastic synsdromes
Catherine Cargo (United Kingdom)
14:15–15:15 Oral Abstract Session 1: Genomics of MPN, MDS and AML
Chair to be announced
- DECODING THE MYELOID DISEASE CONTINUUM: MACHINE LEARNING–BASED DEVELOPMENT AND VALIDATION OF A MULTIMODAL INTEGRATING CLASSIFICATION OF MYELOID NEOPLASMS
Yu-Hung Wang (Taiwan) - COMPREHENSIVE CHARACTERIZATION OF SOMATIC PTPN11-MUTATED JMML
Edoardo Muratore (Italy) - LONGITUDINAL COMPREHENSIVE ANALYSIS OF CLONAL EVOLUTION AND TRANSCRIPTOMIC CHANGES TO UNRAVEL DISEASE PERSISTENCE AND EVOLUTION IN MPN
Conrad Weidt (Germany) - LONG-READ TRANSCRIPTOMICS DEFINES SPLICING DEFECTS IN DDX41-MUTATED ACUTE MYELOID LEUKEMIA
Carolin Seeling (Germany)
15:15–15:30 Coffee break
15:30–16:30 Session 2: Future Diagnostic Platforms and Educational Needs – Data Overload
Torsten Haferlach (Germany) & Matteo Della Porta (Italy)
- From Data Overload to Better Care: How AI can improve diagnosis and treatment
Torsten Haferlach (Germany) - Digital twins powered by real-world data for explainable and trustworthy personalized medicine
Matteo Della Porta (Italy)
16:30–17:15 Debate: What to do with an elderly fit patient?
Chair to be announced
- How can we define fitness in 2026?
Adriano Venditti (Italy) - Standards and emerging options for less intensive therapy in 2026
Christoph Röllig (Germany)
17:15–17:30 Coffee break
17:30–18:15 Satellite symposium 1
18:15–19:15 Welcome Reception + Poster session
08:00–08:45 Meet the Experts Breakfast
09:00–10:00 Session 3: Genomics in MPN, MDS, AML
Chair: Paola Guglielmelli (Italy)
- Acute myeloid leukemia
Lars Bullinger (Germany) - Myeloproliferative neoplasms
Paola Guglielmelli (Italy) - Myelodysplastic synsdromes
Matteo Della Porta (Italy)
10:00–11:00 Session 4: Microenvironment, proteomics, and microbiome
Chair: Dominique Bonnet (United Kingdom)
- Niche
Dominique Bonnet (United Kingdom) - Microbiome
Saeed Shoaie (United Kingdom) - Proteims and metabolomics
Speaker to be announced
11:00–11:15 Coffee break
11:15–12:15 Session 5: Immunome in MPN, MDS and AML – What Is It and How to Target?
Chairs: Shahram Kordasti (United Kingdom) & Arjan van de Loosdrecht (Netherlands)
- Overriding intrinsic inflammation in AML as a therapeutic concept
Philipp Jost (Austria) - Myeloproliferative neoplasms and CHIP
Dominik Wolf (Austria) - Myelodysplastic synsdromes
Arjan van de Loosdrecht (Netherlands)
12:15–13:30 Lunch break
13:00–13:45 Satellite Symposium 2
13:45–14:45 Session 6: Treatment of MPN in 2026
Chairs: Claire Harrison (United Kingdom) & Jean-Jacques Kiladjian (France)
- CALR antibody treatment
Claire Harrison (United Kingdom) - MRD included
Jean-Jacques Kiladjian (France) - Transplant in MPN
Donal McLornan (United Kingdom)
14:45–15:00 Coffee break
15:00–16:00 Session 7: Treatment of MDS in 2026
Chairs: Antonio Almeida (Portugal) & Lionel Ades (France)
- Low-risk
Antonio Almeida (Portugal) - High-risk
Maria Teresa Voso (Italy) - Novel agents
Lionel Ades (France)
16:00–16:45 Debate: Immunotherapy in MDS, a finished story?
Chair: Arjan van de Loosdrecht (Netherlands)
- Debaters
Shahram Kordasti (United Kingdom)
Lionel Ades (France)
16:45–17:00 Coffee break
17:00–17:45 Satellite Symposium 3
09:00–10:00 Session 8: Treatment of AML in 2026
Chair: Konstanze Döhner (Germany)
- Combination therapy using novel drugs for patients fit for intensive therapy
Bas Wouters (Netherlands) - Combination therapy using novel drugs for patients unfit for intensive therapy
Alessandro Isidori (Italy) - Novel aspects of MRD monitoring
Konstanze Döhner (Germany)
10:00–11:00 Oral Abstract Session 2
Chair to be announced
- CLINICAL AND MOLECULAR FEATURES OF THERAPY-RELATED AML: A HARMONY PROJECT ANALYSIS
Luca Guarnera (Italy) - SINGLE-CELL MULTI-OMICS REVEALS DISEASE-SPECIFIC REGULATORY T CELL SUBPOPULATIONS IN MYELODYSPLASTIC NEOPLASMS
Rita Antunes dos Reis (United Kingdom) - SURVIVAL BENEFIT OF ALLOGENEIC HSCT IN CMML PATIENTS DURING THE MOLECULAR STRATIFICATION ERA
Rui Ma (China) - IMMUNE MODULATION IN MYELOPROLIFERATIVE NEOPLASMS: DEVELOPMENT OF A MACROPHAGE PHAGOCYTOSIS ASSAY AND ANALYSIS OF TUMOUR-MACROPHAGE INTERACTIONS
Anya Megan Squires (United Kingdom) - HYDROXYUREA-DRIVEN TP53 HEMIZYGOSITY ACCELERATES LEUKEMIC TRANSFORMATION IN CALR-MUTANT MPNS
Syrine Bel Haj Yahia (France)
11:00–11:15 Coffee break
11:15–12:00 Session 9: Challenging Clinical Cases
Chairs: Alesia Khan (United Kingdom) & Sanam Loghavi (United States)
- MDS/MPN (case)
Alesia Khan (United Kingdom) - Hematopathologist review
Sanam Loghavi (United States) - Expert panel
All speakers
12:00–12:15 Closing ceremony
- Closing remarks
Konstanze Döhner (Germany)
Claire Harrison (United Kingdom)
Shahram Kordasti (United Kingdom)
12:15–13:00 Farewell lunch