Scientific and educational activities

Horizon 2020-funded clinical trials in hematology

The SWG was involved in the following trials.

RESILIENCE

A trial to evaluate remote ischemic conditioning for preventing anthracycline cardiotoxicity in lymphoma patients, incorporating a significance focus on the quality of life.

RESOLVE

A project to establish the predictive value of measurable residual disease (MRD) in AML/CLL patients.

It aims to do this through:

  • The development of an MRD registry
  • The establishment of a multicenter, randomized controlled pragmatic trial of standard intensity versus reduced intensity consolidation treatment in MRD-negative patients

The latter will involve individuals with AML (360 patients; five time points) or CLL (134 patients; five time points).

IMPACT

An international, multicenter, randomized pragmatic clinical trial that will compare standard chemotherapy to low-intensity therapy in relapsed or refractory AML patients

International projects involving the SWG

The SWG has been involved in the:

  • Acute Leukemia Advocates Network (ALAN) survey
  • Associazione Italiana Pazienti Sindrome Mielodisplastica (AIPASIM) survey