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Novel basis for chemoresistance in AML: DNMT3A R882 mutations promote chemoresistance and residual disease through impaired DNA damage sensing
Although most acute myeloid leukemia (AML) patients initially respond to chemotherapy, the majority subsequently relapses and succumbs to refractory disease. Residual leukemic cells that survived chemotherapy may persist over time and later cause the disease to come back.
Read moreNew GFI1B variants in bleeding and platelet disorders
Platelets restrict blood loss upon vessel damage by formation of a clot (thrombus). Recently, we reported a family with a bleeding and platelet disorder (BPD), which was caused by a defect in the gene GFI1B1.
Read moreEvidence and policy to ensure good clinical practice
Interview with Vinay Prasad MD MPH by Heiko Becker MD, on behalf of YoungEHA
Leaders in the field that have the potential to make a difference, that challenge the way we are doing things, who push our perspective out of our…
What can I expect?
Learning Objectives
To have a greater understanding of computational techniques as applied to haematological datasets,
To improve personal computational biology skillset, tailored to the project,
To further develop and widen your network of potential collaborators, both in terms of peer group and…
Highlights from the SWG
The SWG organized a EHA scientific workshop entitled: “Shaping the future of MSC Therapy” in Amsterdam from November 23-25, 2017.
Read moreEHA undersigns Manifesto on Treatment Optimization
EHA has given its formal endorsement to the “Manifesto for a new approach for better medicine in Europe: Establishing Treatment Optimization as part of personalized medicine development”.
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