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Novel basis for chemoresistance in AML: DNMT3A R882 mutations promote chemoresistance and residual disease through impaired DNA damage sensing
Although most acute myeloid leukemia (AML) patients initially respond to chemotherapy, the majority subsequently relapses and succumbs to refractory disease. Residual leukemic cells that survived chemotherapy may persist over time and later cause the disease to come back.
Read moreNew GFI1B variants in bleeding and platelet disorders
Platelets restrict blood loss upon vessel damage by formation of a clot (thrombus). Recently, we reported a family with a bleeding and platelet disorder (BPD), which was caused by a defect in the gene GFI1B1.
Read moreThe European Union must deliver funding for research of blood disorders
At the 20th Annual Congress of EHA, the results of two major projects are presented. The first is a study into the Cost of Blood Disorders in the EU Member States and Norway, Iceland, and Switzerland.
Read moreJesus San Miguel presents the Ham-Wasserman Lecture at the 2014 ASH Annual Meeting
Professor San Miguel is a member of the Advisory board of the International Myeloma Foundation and the Multiple Myeloma Research Foundation.
Read moreAnnouncement: The award winners of the prestigious EHA-ASH Translational Research in Hematology Training Award are selected
The winners of the TRTH 2015 Awards are:
Name
Nationality
Name
Nationality
Ileana Antony-Debre
French
Jean-Baptiste Micol
French
Pavan Bachireddy
American
Christopher Ott
American
Lucile Couronné
French
Carsten Riether
German
Moniek de Witte
Dutch
Anindita Roy
British
Ammon Fager
American
Melody Smith
American
Gillian Horne
British
Zuzana Tothova
Slovakian
Moonjung Jung
South Korea
Marcin Wlodarski
Polish
Jonas Samuel Jutzi
Swiss - German
Yuh-Ying Yeh
Taiwanese
Milka Koupenova-Zamor
American - Bulgarian
Sasan Zandi
Iranian
Marwan Kwok
British
Patricia Maiso
Spain
Are you interested in joining the…
First Horizon 2020 Work Programme update – budget, and launch of FTI and innovation prizes
Click here for the PDF.
Read moreThe importance of education and collaboration for the treatment of patients
This article is written in the context of EHA’s membership of the European Alliance for Personalised Medicine (EAPM) where EHA takes a lead in the development of a strategy for education in personalized medicine. Read the full article here
Read moreABT-199: Novel Bcl-2 specific inhibitor updated results confirm substantial activity and durable responses in high-risk CLL.
Chronic Lymphocytic Leukaemia (CLL) is the most common leukemia in adults in the Western world and is diagnosed in approximately 5 persons per 100,000 population per year.
Read moreDo generics of imatinib jeopardize patient safety for the sake of saving money? An experience in Turkish patients.
The high cost of tyrosine kinase inhibitors developed for chronic myeloid leukemia is a major concern for the health care payers, especially in countries with restricted resources.
Gdf -11 a new target to improve anemia in thalassemia.
β-thalassemias are characterized by ineffective red blood cell (RBC) production, leading to anemia, iron overload, and organ failure. As current treatment options for β-thalassemia are limited, there is a clear unmet need for alternative therapies.
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