EHA-SWG Scientific Meeting on From Aging Hematopoietic Stem Cells to Age-related Diseases: Opportunities for Intervention

Dates: November 13-15, 2025
Location: Barcelona, Spain
Chairs: M Essers, E Laurenti, S Valletta, K Kirschner
Collaborating SWG: EHA Specialized Working Group (SWG) on Stem Cells and SWG on Aging

Registration will be open soon

Join leading experts in hematopoietic stem cell (HSC) biology and aging, and clinical care for a comprehensive workshop addressing age-related hematologic disorders. This event bridges cutting-edge science with clinical practice, fostering collaboration between researchers, clinicians, and patient advocates. These communities will merge their knowledge to share a program that ranges from basic scientific topics on HSC biology to clinical research on therapeutic and preventive strategies. 

Program

The program will join basic research on understanding HSC biology and aging process to the care of hematologic disorders in the elderly and in individuals at risk of aging-related disorders. 

Key topics will include: 

  • Advances in understanding HSC aging, senescence, and clonal hematopoiesis
  • Biomarkers of aging and disease progression, including clocks for predicting aging and longevity
  • The impact of immunosenescence and inflammaging on clonal outgrowth, aging and disease
  • Cellular senescence and the impact of senolytics to eliminate senescent cells
  • Strategies for identifying at-risk individuals and developing preventive therapies 

The scientific need for this meeting arises from the HSC aging community and practicing clinicians often operating in silos, with limited opportunities for fruitful interaction, especially at the more junior level.  

Capped to 60 participants, this workshop will include a mix of lectures and dynamic discussions. All selected applicants will be invited to present their research, covering the following topics:

  1. Hematopoietic stem cell aging (mechanism, intrinsic and extrinsic regulators)
  2. Age-related senescence
  3. Clonal hematopoiesis
  4. Biomarkers of aging
  5. Age-related interventions and clinical trials

Learning objectives

After attending this meeting, participants will be able to: 

  • Gain insights into how hematopoietic cells and the bone marrow
  • Understand how microenvironment change with age, and how these changes contribute to aging and age-related diseases
  • Understand the pathophysiology of hematologic disorders in the elderly
  • Discuss the last experimental models used to study aging of the hematopoietic system
  • Understand the challenge of identifying individuals at highest risk of age-related hematologic disorders, and the strategies to mitigate this risk
  • Identify the barriers for clinical data generation in the aging population 

Target audience

The meeting is intended for hematologist-oncologists, non-malignant hematologists, transplant specialists, research scientists and patient advocates. 

Meeting categories

Basic, Translational and Clinical 

EHA Curriculum sections covered

Primary

Cellular and molecular biology of hematopoietic cells. Management of elderly and unfit patients. 

Secondary

BM failure. Myeloid malignancies: Pre-malignant clonal cytopenias, Myeloproliferative neoplasms, MDS/MPNs, Myelodysplastic syndromes, AML. Lymphoid malignancies: B-cell neoplasms, T-cell and NK-cell neoplasms, Hodgkin lymphoma. Treatment of hematologic conditions: Specific treatments, Transplantation and cellular therapies, Prevention and treatment of infectious diseases, Supportive care. 

Registration 

Registration will be open soon.

Abstract & clinical case submission

Abstract & clinical case submission is an important part of this meeting. The submission will be open soon.

Venue

H10 Marina Barcelona
Olympic Village, Av. del Bogatell, 64-68, Sant Martí,
08005 Barcelona
Spain

EBAH

EBAH accredited stamp DEF2

Continuing Medical Education (CME) is widely accepted to encourage individual practitioners to maintain and develop professional knowledge and skills keeping up-to-date with latest developments within the field. The meeting will be accredited by the EBAH system. Participants of this meeting are eligible to receive one Continuing Medical Education (CME) credit point for every hour of accredited activity from the EBAH system. 

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