Postdoctoral position in leukemia research

01/31/21   Austria   Division of Hematology, Medical University of Graz  

Job description

Identifying and targeting early molecular events in leukemogenesis.

The Reinisch Lab at the Division of Hematology, Department of Internal Medicine, Medical University of Graz, Austria is seeking a highly motivated, skilled,  and energetic candidate to fill an open postdoctoral position (fulltime) for studying basic cancer biology with a particular focus on leukemia and the contribution of individual somatic mutations in early leukemogenesis.

This project will likely involve CRISPR/Cas9-genome editing, functional analyses, targeted and/or genome-wide CRISPR-screens,  and single-cell RNA-Sequencing of human leukemic stem cells.

Our group utilizes state-of-the-art technologies  (1) to understand early somatic mutations in the process of leukemic transformation of hematopoietic stem and progenitor cells (2) to characterize the molecular mechanism involved in early leukemogenesis and (3) to find potential druggable new targets to eradicate leukemic stem cells.

The successful postdoc researcher will join a collaborative, energized, and collegial group. Successful applicants will have the opportunity to tailor their project related to the above topic to individual interests and skills with the PI.

The applicant will be fully employed for 3 years and insured (accident, health, pension) A monthly salary according to the guidelines of the Austrian Science Fund (FWF) will be offered.

 

 

Requirements

The applicant should have a doctoral degree in biomedical science (PhD or MD/PhD), a good publication record, excellent writing/communication skills,  and a strong background in molecular biology and cell biology. Preference will be given to individuals with profound expertise in molecular cloning and genome engineering using CRISPR/Cas9, and hands-on experience with flow-cytometry, hematopoietic stem cell culture, and gold-standard in vitro and in vivo hematopoietic assays.

How to apply

Interested candidates should submit their curriculum vitae, statement of research interests via e-mail to Dr. Andreas Reinisch, PhD (a.reinisch@medunigraz.at)